NCT07004634

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

Comparison of the Application Effects of Different Drainage Modes in the Perioperative Period of Minimally Invasive Three-Field Radical Esophagectomy for Esophageal Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

Conditions

• Esophageal Cancer
• Drainage/Methods
• Postoperative Pain

Interventions

Type	Name	Description
PROCEDURE	Chest mediastinal tube	Transthoracic mediastinal drainage was performed for postoperative management of the patient.
PROCEDURE	Abdominal mediastinal tube	Transperitoneal mediastinal drainage was performed for postoperative management of the patient.
PROCEDURE	Chest tube + chest mediastinal tube	Chest tube insertion combined with transthoracic mediastinal drainage was performed for postoperative management of the patient.

Timeline

• Start date: 2025-04-30
• Primary completion: 2026-05-01
• Completion: 2026-08-01
• First posted: 2025-06-04
• Last updated: 2025-06-10

Locations

1 site across 1 country: China