NCT07002944

Pulsed Radiofrequency of Shoulder Individual Nerves Versus Brachial Plexus in Management of Chronic Post Mastectomy Shoulder Pain

Role of Pulsed Radiofrequency of Shoulder Individual Nerves Versus Brachial Plexus in Management of Chronic Post Mastectomy Shoulder Pain: A Prospective Randomized Controlled Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

this study aims to assess the role of pulsed radiofrequency of the brachial plexus or pulsed radiofrequency of shoulder individual nerves in the management of post-mastectomy shoulder pain.

Detailed description

Breast cancer is the second most common cancer world-wide following lung cancer. It afflicts about 1.7 million patients annually, of which 60% mandate surgery of the breast and/or the axilla, and nearly 20-50% of them may develop post-mastectomy pain syndrome. Regarding pulsed RF of the brachial plexus, it is not tried up till now for shoulder pain. Since C 5,6,7 are derived from upper and middle trunks of brachial plexus, then innervation of shoulder joint can be blocked by interscalene brachial plexus block or pulsed radiofrequency . Review of literature demonstrated efficacy of PRF of brachial plexus in case studies for other conditions e.g. pain associated with a tumor involving the brachial plexus , refractory stump pain , chemotherapy-induced peripheral neuropathy of the upper limb and radiation-induced brachial plexopathy .

Conditions

• Pulsed Radiofrequency
• Shoulder Individual Nerves Brachial Plexus
• Chronic
• Post Mastectomy
• Shoulder Pain

Interventions

Type	Name	Description
OTHER	Brachial plexus pulsed radiofrequency	Patients will receive pulsed radiofrequency of brachial plexus with steroids injection.
OTHER	Sholder individual nerves pulsed radiofrequency	Patients will receive shoulder individual nerves pulsed radiofrequency with steroids injection.
OTHER	Control	Patients will receive conservative treatment (paracetamol 1000 tid and pregabalin 75 mg bid; can be increased to 150 mg bid , oxycodone 10 mg oral every 12 hrs .

Timeline

• Start date: 2025-06-03
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2025-06-04
• Last updated: 2025-06-04

Locations

1 site across 1 country: Egypt