NCT06993948

Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 235 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study aimed to evaluate the cause and prognosis of hyperdynamic left ventricular ejection fraction in critically ill patients with sepsis.

Detailed description

Cardiovascular dysfunction is increasingly being recognized as a significant complication in sepsis, affecting patient outcomes. Among the key parameters used to evaluate cardiac performance is the left ventricular ejection fraction (LVEF), typically assessed via transthoracic echocardiography (TTE). LVEF has been extensively studied; most investigations into preserved ejection fraction tend to group all values ≥50% together, thereby overlooking the potential clinical implications of LVEF ≥70%, often referred to as hyperdynamic LVEF (HDLVEF).

Conditions

• Hyperdynamic
• Left Ventricular Ejection Fraction
• Mortality
• Intensive Care Unit
• Septic Shock

Interventions

Type	Name	Description
DEVICE	Transthoracic echocardiography	Transthoracic echocardiography (TTE) was carried out. The assessment of left ventricular ejection fraction (LVEF) relied primarily on two-dimensional echocardiography using visual estimation.

Timeline

• Start date: 2022-08-01
• Primary completion: 2023-07-01
• Completion: 2023-07-01
• First posted: 2025-05-29
• Last updated: 2025-05-29

Locations

1 site across 1 country: Egypt