NCT06991231

The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty

The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty - A Randomized Prospective Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 215 (estimated)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy of cryoablation use on patient-reported outcomes (PROMs) and opioid consumption following total knee arthroplasty. This is a randomized study that will involve a 1:1 randomization to total knee arthroplasty +/- cryoablation.

Conditions

• Post-Operative Pain
• Total Knee Arthroplasty

Interventions

Type	Name	Description
PROCEDURE	Total knee arthroplasty (TKA)	Administered as part of patient standard of care.
DEVICE	Cryoablation	Cryoablation will be administered on the leg of the knee indicated for surgery.

Timeline

• Start date: 2025-06-13
• Primary completion: 2026-09-01
• Completion: 2027-01-01
• First posted: 2025-05-27
• Last updated: 2026-04-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study