Trials / Recruiting
RecruitingNCT06985225
Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Severe Asthma
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 5 (estimated)
- Sponsor
- University of Kansas Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will be identified using CT imaging, and xenon MRI will be used to evaluate ventilation and gas exchange impairments in regions of the lungs corresponding to the airways downstream of mucus plugs.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| COMBINATION_PRODUCT | Hyperpolarized 129 Xenon | Xenon gas contrast agent for MRI |
Timeline
- Start date
- 2025-06-01
- Primary completion
- 2026-12-01
- Completion
- 2026-12-01
- First posted
- 2025-05-22
- Last updated
- 2025-05-22
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT06985225. Inclusion in this directory is not an endorsement.