NCT06978595

Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies

Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies: a Retrospective Cohort Based on SEER Database From 2000-2021

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 8,171 (actual)
• Sponsor: asmaa salama ibrahim · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This original research investigates the critical issue of gastrointestinal (GI) second primary malignancies (SPMs) in patients with signet ring cell carcinoma (SRCC), a rare and aggressive subtype of colorectal cancer. Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, the investigators assessed the risk of GI SPMs, particularly within 2-11 months post-SRCC diagnosis.

Conditions

• Colorectal Carcinoma
• Cancer
• Signet Ring Adenocarcinoma of the Colon

Timeline

• Start date: 2000-01-01
• Primary completion: 2021-12-30
• Completion: 2021-12-30
• First posted: 2025-05-18
• Last updated: 2025-05-18

Locations

1 site across 1 country: Egypt