Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT06966479

A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)

A Long-Term Extension Study to Evaluate Safety and Efficacy of Verekitug (UPB-101) in Adult Participants With Severe Asthma Who Completed the VALIANT Trial

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
396 (actual)
Sponsor
Upstream Bio Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to evaluate the long-term safety and efficacy of verekitug (UPB-101) in participants who complete the VALIANT study (NCT06196879).

Conditions

Interventions

TypeNameDescription
DRUGVerekitugVerekitug subcutaneous injection.
DRUGPlaceboVerekitug matching placebo.

Timeline

Start date
2025-05-21
Primary completion
2027-09-01
Completion
2027-09-01
First posted
2025-05-11
Last updated
2026-04-02

Locations

102 sites across 15 countries: United States, Argentina, Bulgaria, Canada, Chile, Czechia, Germany, Italy, Japan, Poland, South Africa, South Korea, Spain, Ukraine, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06966479. Inclusion in this directory is not an endorsement.