NCT06966011

Rebound Pain After Peripheral Nerve Blocks in Total Knee Arthroplasty

Pain Management After Total Knee Arthroplasty: Incidence and Outcomes of Rebound Pain

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 294 (actual)
• Sponsor: Konya City Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This prospective observational study aims to determine the incidence and clinical impact of rebound pain after peripheral nerve blocks in patients undergoing total knee arthroplasty. Rebound pain is defined as a sudden, severe pain (NRS ≥7) emerging after block resolution. Primary outcome is the incidence of rebound pain; secondary outcomes include pain severity, rescue analgesia use, nausea, vomiting, sleep quality, and patient satisfaction.

Conditions

• Total Knee Arthroplasty
• Postoperative Pain
• Rebound Pain
• Peripheral Nerve Block
• Pain Management

Timeline

• Start date: 2025-05-21
• Primary completion: 2026-03-03
• Completion: 2026-03-03
• First posted: 2025-05-11
• Last updated: 2026-04-03

Locations

1 site across 1 country: Turkey (Türkiye)