NCT06958354

Evaluation of the Clinical Relationship Between Procalcitonin Level and Bacteremia Agent in Intensive Care Unit Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,529 (actual)
• Sponsor: Gulhane Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

In intensive care units, sepsis, which can be defined as bacteremia and the irregular and uncontrolled inflammatory response to it, is one of the most important causes of mortality. Early recognition of sepsis and appropriate antibiotic use for the causative agent is one of the most important steps in the fight against sepsis. Procalcitonin (PCT) is a calcitonin precursor peptide and has been reported to predict bacteremia early. While the PCT concentration level is negligible in healthy individuals, it has been shown to increase especially in bacterial infections, sepsis, trauma and burns. In our study, our aim is to determine whether there is a relationship between serum PCT concentration levels taken within 24 hours according to the time of the sample taken for blood culture with growth in patients followed up in our Internal Intensive Care Unit.

Conditions

• Sepsis
• Septic
• Bacteremia and Sepsis
• Intensive Care Medicine
• Procalcitonin

Timeline

• Start date: 2023-03-15
• Primary completion: 2025-01-01
• Completion: 2025-10-19
• First posted: 2025-05-06
• Last updated: 2025-12-11

Locations

1 site across 1 country: Turkey (Türkiye)