NCT06956638

Bilirubin Levels to Diagnose Appendicitis and Predict Appendiceal Perforation

Predictors of Appendiceal Perforation and the Role of Total Bilirubin at Presentation: A Single Center Prospective Cross-sectional Study in Nepal

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 98 (actual)
• Sponsor: Nepalese Army Institute of Health Sciences · Academic / Other
• Sex: All
• Age: 5 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to learn if serum bilirubin levels can aid in the diagnosis of acute appendicitis and predict appendiceal perforation

Detailed description

The study aims to assess hyperbilirubinemia: serum direct, indirect and total bilirubin to enhance the diagnostic accuracy of acute appendicitis. Also it aims to analyze different patient variables such as age, gender, duration of symptoms, leukocyte and neutrophil count, Alvarado score, presence of fever, nausea \& vomiting, peritonitis alongside serum total bilirubin level in patients with appendicitis and assess which variables can be taken as independent factors to predict appendiceal perforation.

Conditions

• Acute Appendicitis
• Appendicitis Perforated

Interventions

Type	Name	Description
OTHER	Non-interventional	Non-interventional study

Timeline

• Start date: 2022-07-16
• Primary completion: 2023-06-15
• Completion: 2025-03-12
• First posted: 2025-05-04
• Last updated: 2025-05-07

Locations

1 site across 1 country: Nepal