NCT06947785

Effectiveness of Combined Neural Mobilization With Manual Myofascial Release for Sciatic Pain Relief

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Riphah International University · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This study will address to evaluate and compare both Neural mobilization and Manual Myofascial Release of piriformis and Lumbar muscles in sciatic pain with the aim of evaluating and identifying the most effective intervention for managing this specific condition, and provide valuable insights into the effectiveness, mechanisms, and practical considerations associated with these interventions, ultimately contributing to evidence based and patient centered care.

Detailed description

MFR is a hands-on technique targeting fascial restrictions that may contribute to pain and reduced mobility. Barnes proposed that releasing fascial adhesions can improve circulation, reduce nerve compression, and enhance tissue flexibility. In a study by Ajimsha et al. , MFR was found to significantly reduce pain and improve physical function in patients with nonspecific low back pain. There is a lack of comparative research assessing the relative efficacy of neural mobilization andMFR in sciatic pain management. While both techniques are rooted in distinct mechanisms neural desensitization versus fascial release they may have overlapping benefits in improving mobility and reducing pain. This study addresses this research gap by directly comparing the two approaches in individuals with sciatic pain.

Conditions

• Sciatica

Interventions

Type	Name	Description
OTHER	Combined Neural Mobilization with Manual myofascial Release	Combined neural mobilization with manual myofascial release will be provided to each subject.
OTHER	Neural Mobilization	neural mobilization will be provided to each subject.
OTHER	Manual Myofascial Release	Manual myofascial release will be provided to each subject.

Timeline

• Start date: 2025-04-15
• Primary completion: 2025-10-03
• Completion: 2025-12-31
• First posted: 2025-04-27
• Last updated: 2026-04-08

Locations

1 site across 1 country: Pakistan