NCT06909500

A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users

ACT on Vaping: Digital Therapeutic for Young Adult Vaping Cessation

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,372 (estimated)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

This clinical trial evaluates a smartphone application (app) called Acceptance and Commitment Therapy (ACT) on Vaping for helping young adults quit using electronic cigarettes (e-cigarettes). E-cigarettes pose numerous risks, particularly to youth and young adults. Addressing the high prevalence of e-cigarette use by young adults requires effective and accessible treatments to support current users to quit. Research shows this group prefers and benefits from newer methods of treatment delivery such as digital interventions. ACT on Vaping is a digital therapeutic intended to deliver behavioral therapy to young adults who vape to motivate and support abstinence from all nicotine and tobacco products. The app contains sessions that promote awareness of cues that trigger tobacco use and teach skills for responding to these triggers in a way that is tailored for the participant's readiness to quit. Receiving access to the ACT on Vaping app may be effective in helping young adults quit vaping.

Detailed description

OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants use the ACT on Vaping app (Version A) and receive a text messaging program to motivate and support quitting. Participants also receive incentivized text message check-ins at 2 weeks, 2 months, and 4 months to assess their vaping status. ARM II: Participants use the ACT on Vaping app (Version B) and receive incentivized text message check-ins at 2 weeks, 2 months, and 4 months to assess their vaping status. After completion of study intervention, participants are followed up at 3 and 6 months.

Conditions

• Nicotine Dependence
• Tobacco-Related Carcinoma

Interventions

Type	Name	Description
BEHAVIORAL	Smartphone app	Receive access to the ACT on Vaping app
BEHAVIORAL	Smartphone app	Receive access to the ACT on Vaping app
OTHER	Text Message	Receive incentivized text messages to access vaping status
OTHER	Text Message	Receive intervention text messages
OTHER	Survey Administration	Ancillary studies

Timeline

• Start date: 2026-04-30
• Primary completion: 2027-10-31
• Completion: 2027-10-31
• First posted: 2025-04-03
• Last updated: 2026-04-13

Locations

1 site across 1 country: United States