NCT06900894

Effects of Platelet-Rich Fibrin and Kinesio Taping on Postoperative Recovery in Oral Surgery

Effectiveness of Platelet-Rich Fibrin and Elastic Bandaging on Postoperative Pain, Edema, and Recovery Following Impacted Molar Surgery: A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Mustafa Kemal University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the effectiveness of Platelet-Rich Fibrin (PRF) and Kinesio Taping in reducing postoperative pain, edema, and improving recovery following impacted third molar surgery. A prospective, randomized clinical trial was conducted with 44 patients aged 18-35 years. Patients were assigned to three groups: (1) PRF applied locally to the extraction socket, (2) Kinesio Taping applied postoperatively and removed on the third day, and (3) a control group receiving standard postoperative care. Postoperative outcomes were assessed on days 3 and 7, including pain levels, edema, and quality of life. This study aims to evaluate PRF and Kinesio Taping as non-pharmacological adjuncts in oral and maxillofacial surgery.

Detailed description

This study investigates the effectiveness of Platelet-Rich Fibrin (PRF) and Kinesio Taping in postoperative management following impacted mandibular third molar surgery. Postoperative complications, such as pain and edema, are commonly observed and may impact patient comfort and recovery. This study aims to evaluate the feasibility of two non-pharmacological approaches-PRF and Kinesio Taping (Elastic Bandaging)-in postoperative care. A total of 44 patients aged 18-35 years participated in this prospective, randomized clinical trial. Patients were assigned to one of three groups: PRF Group: Platelet-rich fibrin (PRF) was applied locally into the extraction socket. Kinesio Taping Group: An elastic bandage was applied postoperatively to the surgical area and removed on the third day. Control Group: Standard postoperative care was provided with no additional intervention. Postoperative evaluations were conducted on the 3rd and 7th days. The measured parameters included: Edema: Measured using anthropometric techniques. Pain: Assessed with the Numerical Rating Scale (NRS). Quality of Life: Evaluated using the Oral Health Impact Profile-14 (OHIP-14). This study aims to assess the feasibility of PRF and Kinesio Taping in postoperative management.

Conditions

• Impacted Third Molar Tooth
• Postoperative Pain
• Postoperative Edema

Interventions

Type	Name	Description
BIOLOGICAL	Platelet-Rich Fibrin (PRF)	PRF was prepared using a centrifugation protocol and applied to the extraction socket.
DEVICE	Kinesio Taping	Kinesio Tape was applied postoperatively to the masseter and submandibular region.
OTHER	Standard Postoperative Care	Patients in the control group received standard postoperative care.

Timeline

• Start date: 2023-10-01
• Primary completion: 2024-01-10
• Completion: 2024-05-21
• First posted: 2025-03-28
• Last updated: 2025-04-02

Locations

1 site across 1 country: Turkey (Türkiye)