Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06885034

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

A Phase 1b/2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of GSK5764227 Alone and in Combination in Participants With Previously Treated Advanced Unresectable or Metastatic Gastrointestinal Solid Tumors

Status
Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
320 (estimated)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will check how well a new medicine, GSK5764227, works, how safe it is and how the body handles it in participants all around the world with advanced inoperable or metastatic gastrointestinal cancer who have previously received treatment.

Conditions

Interventions

TypeNameDescription
BIOLOGICALGSK5764227GSK5764227 will be administered

Timeline

Start date
2025-06-11
Primary completion
2027-11-11
Completion
2028-06-23
First posted
2025-03-19
Last updated
2025-11-18

Locations

47 sites across 14 countries: United States, Australia, Belgium, Brazil, Canada, France, Italy, Japan, Netherlands, Norway, Poland, South Korea, Spain, Sweden

Regulatory

Source: ClinicalTrials.gov record NCT06885034. Inclusion in this directory is not an endorsement.