NCT06879483

Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

Early and Intermediate Term Outcomes of Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Thoraco-laparoscopic partial esophagogastrectomy has emerged as a promising minimally invasive alternative, combining thoracoscopy and laparoscopy to reduce the trauma associated with open surgery.Early and intermediate-term outcomes provide critical information on both the oncological efficacy and functional benefits of the procedure. By examining recurrence rates within the first 12-24 months, this study will provide valuable insights into the oncological robustness of this approach compared to more invasive approaches.

Conditions

• Esophageal Cancer

Interventions

Type	Name	Description
PROCEDURE	Thoraco-laparoscopic partial esophagogastrectomy	1. Laparoscopic Phase: * The stomach is mobilized, and a part of it is resected to include the lower esophageal segment. * Left gastric nodes, the splenic and common hepatic nodes are dissected. * A gastric tube is created using endoscopic staplers for esophageal reconstruction and fixed to the proximal gastrectomy specimen using sutures 2. Thoracoscopic Phase: * The patient is positioned in prone position * Three small incisions are made in the thorax * Further esophageal mobilization through a right thoracoscopy is performed in left lateral decubitus. Periesophageal nodes are retrieved en bloc. Left and right paratracheal and subcarinal lymph nodes are resected separately. The esophagus is transected at the tumor's proximal margin. 3. Reconstruction: * An anastomosis (esophagogastric connection) is performed to restore continuity, typically using a circular stapler or hand-sewn technique.

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-09-01
• Completion: 2027-09-01
• First posted: 2025-03-17
• Last updated: 2025-03-17

Locations

1 site across 1 country: Egypt