NCT06876116

Once-daily Fluorometholone vs Twice-daily Cyclosporine in Dry Eye Disease

Comparison of Therapeutic Effects of Once-daily Fluorometholone 0.1% Versus Twice-daily Cyclosporine 0.05% in Patients With Dry Eye Disease: A Randomized, Assessor-blinded Clinical Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Korea University Anam Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study compares the therapeutic effects of once-daily fluorometholone 0.1% versus twice-daily cyclosporine 0.05% after short-term fluorometholone induction treatment in dry eye disease.

Conditions

• Dry Eye Disease (DED)

Interventions

Type	Name	Description
DRUG	Fluorometholone 0.1% ophthalmic solution	After induction therapy with fluorometholone 0.1% four times a day for 4 weeks, patients continued with fluorometholone 0.1% once a day for 8 weeks.
DRUG	Cyclosporine 0.05% eye drops	After induction therapy with fluorometholone 0.1% four times a day for 4 weeks, patients continued with cyclosporine 0.05% twice a day for 8 weeks.

Timeline

• Start date: 2022-09-01
• Primary completion: 2024-03-01
• Completion: 2024-05-24
• First posted: 2025-03-14
• Last updated: 2025-03-14

Locations

1 site across 1 country: South Korea