NCT06873737

Analysis of the Levels of HLADR+ Extracellular Vesicles in Women With Preeclampsia as a Early Potential Biomarker

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Analysis of the circulating levels of placenta-derived HLA-DR+ extracellular vesicles in the first, second and third trimester of pregnancy of women with high and low risk to develop preeclampsia.

Detailed description

The aim of this study is to analyze the levels of circulating placenta-derived HLA-DR+ extracellular vesicles in the first, second and third trimester of pregnancy of women with high and low risk to develop preeclampsia to investigate the potential role of HLA-DR as early biomarker.

Conditions

• Preeclampsia

Interventions

Type	Name	Description
OTHER	Blood samples for inflammatory markers	Blood sampling in the first, second, trimester of pregnancy

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-09-30
• Completion: 2026-01-01
• First posted: 2025-03-13
• Last updated: 2025-03-13

Locations

1 site across 1 country: Italy