NCT06848829

Difference of Tear Ferning Between Women with and Without Menopausal.

Difference of Tear Ferning Between Pre-and Post-menopausal Women and Between Post-menopausal Women with or Without Hormone Replacement Therapy (HRT)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Chung Shan Medical University · Academic / Other
• Sex: Female
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Application of tear ferning test for clinical dry eye diagnosis and menopause

Detailed description

Analyzing the difference in tear ferning structure between women pre and post-menopause with and without hormone replacement therapy (HRT). Tear and blood samples were collected for a menopause-related Enzyme-linked immunosorbent assay. Tear volume, tear osmolarity, intraocular pressure, and tear break-up time were also measured for comparison.

Conditions

• Dry Eye Syndromes

Interventions

Type	Name	Description
OTHER	Pre-manepausal women	Compare tear ferning structure between pre-menopause and post-menopause women.

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-09-01
• Completion: 2025-10-01
• First posted: 2025-02-27
• Last updated: 2025-02-27

Locations

1 site across 1 country: Taiwan