NCT06819631

Characterization of Subjective Discomfort in Patients With Tear Dysfunction

Retrospective and Observational Study in Relation to the Subjective Pain of Patients Attending the Corneal and Ocularcsurface Analysis Laboratory (LACSO) Affected by Ocular Surface Dysfunctions

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 12,000 (estimated)
• Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Characterization of subjective discomfort/pain in patients with ocular surface dysfunction in association with clinical and laboratory parameters, for a better understanding of the underlying pathogenic mechanisms.

Detailed description

Dry Eye Disease (DED) is a multifactorial chronic disease impairing the ocular surface. DED can be associated with conditions of inflammation and neurosensory dysfunction. The aim of this study is to characterize the discomfort/pain in subjects affected by DED with the administration of scales, questionnaires, and analysis of corneal sensitivity by keratoesthesiometry, in association with clinical laboratory parameters.

Conditions

• Dry Eye Disease

Timeline

• Start date: 2025-03-01
• Primary completion: 2025-03-01
• Completion: 2029-06-30
• First posted: 2025-02-11
• Last updated: 2025-02-11

Locations

1 site across 1 country: Italy