NCT06814483

Effects Multimodal Mind and Body Approach for MCI

Modulation Effects of a Computer-based Multimodal Mind and Body Approach for Mild Cognitive Decline

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of this application is to develop a computer-based multimodal mind and body approach (CMMBA) for mild cognitive impairment (MCI). This product will provide a new, cost-effective and easily accessible treatment option for MCI and potentially other age-related dementia.

Detailed description

The goal of this Phase I R41 (STTR) application is to develop a computer-based multimodal mind and body approach (cbMMBA) to improve the cognitive function for mild cognitive impairment (MCI). This application, if successful, will provide a cost-effective and easily accessible treatment option for MCI and other age-related dementia, significantly improve the prevention of MCI development, and directly benefit patients suffering from the highly prevalent disorder, particularly for those who may have limited access to in-person mind and body interventions.

Conditions

• Mild Cognitive Impairment

Interventions

Type	Name	Description
BEHAVIORAL	Experimental: A computer-based multimodal mind and body approach (cbMMBA)	cbMMBA will include three modules: BDJ, acupressure, and relaxation techniques including deep breathing, guided imagery, and progressive muscle relaxation.
BEHAVIORAL	A standard cognitive training group	The program uses paper puzzles (Sudoku, crosswords, word-search, etc.) to engage subjects

Timeline

• Start date: 2023-12-11
• Primary completion: 2025-04-11
• Completion: 2025-07-15
• First posted: 2025-02-07
• Last updated: 2026-03-09
• Results posted: 2026-02-02

Locations

1 site across 1 country: United States