NCT06807697

Quality of Life Before and After Radiotherapy in Patients With Head and Neck Cancer

A Pilot Investigation of the Quality of Life Before and After Radiotherapy in Patients With Head and Neck Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: University of Turin, Italy · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Worldwide, head and neck cancers (HNCs) are widespread (650,000 cases per year) and cause more than 330,000 deaths per year. Almost all cases, about 90%, are cancers of the oral cavity, oropharynx, and larynx. In conventional clinical practice, HNCs are treated primarily with radiation therapy (RT), often used in combination with surgery and/or chemotherapy. Like most anti-neoplastic therapies, RT carries significant adverse effects both acute and chronic. Both types of adverse effects have a significant impact on quality of life (QoL). The aim of the study is to examine the worsening of QoL in patients with HNC before and after cancer therapy and to assess the extent that each factor has in its worsening.

Conditions

• Head and Neck Cancer
• Quality of Life (QOL)

Interventions

Type	Name	Description
RADIATION	Curative radiotherapy for Head and Neck Cancers	Radiotherapy is a localized, non-invasive, painless therapy, mostly performed on an outpatient basis, capable of causing necrosis or the death of tumor cells through the use of high-energy radiation called ionizing radiation.

Timeline

• Start date: 2025-01-02
• Primary completion: 2025-04-30
• Completion: 2025-04-30
• First posted: 2025-02-04
• Last updated: 2025-05-11

Locations

1 site across 1 country: Italy