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RecruitingNCT06767683

A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia

An Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Durability of Treatment Effect of ALKS 2680 in Subjects With Narcolepsy Type 1 and Type 2 and Idiopathic Hypersomnia

Status
Recruiting
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
256 (estimated)
Sponsor
Alkermes, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to continue to measure the safety, tolerability, and durability of treatment effect in subjects with Narcolepsy Type 1 (NT1), Narcolepsy Type 2 (NT2), or Idiopathic Hypersomnia (IH) when taking ALKS 2680 tablets.

Conditions

Interventions

TypeNameDescription
DRUGALKS 2680, 4mgOral tablet containing 4 mg of ALKS 2680 for once daily administration
DRUGALKS 2680, 6mgOral tablet containing 6 mg of ALKS 2680 for once daily administration
DRUGALKS 2680, 8mgOral tablet containing 8 mg of ALKS 2680 for once daily administration
DRUGALKS 2680, 10mgOral tablet containing 10 mg of ALKS 2680 for once daily administration
DRUGALKS 2680, 14mgOral tablet containing 14 mg of ALKS 2680 for once daily administration
DRUGALKS 2680, 18mgOral tablet containing 18 mg of ALKS 2680 for once daily administration

Timeline

Start date
2025-01-27
Primary completion
2028-06-01
Completion
2028-06-01
First posted
2025-01-10
Last updated
2026-03-04

Locations

46 sites across 8 countries: United States, Australia, Belgium, Czechia, France, Italy, Netherlands, Spain

Regulatory

Source: ClinicalTrials.gov record NCT06767683. Inclusion in this directory is not an endorsement.