Trials / Recruiting
RecruitingNCT06762795
The HIEnome Study: Genome Sequencing for Perinatal HIE
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- Sponsor
- Baylor College of Medicine · Academic / Other
- Sex
- All
- Age
- 0 Days – 1 Year
- Healthy volunteers
- Not accepted
Summary
Perinatal hypoxic-ischemic encephalopathy is a rare severe condition in which neonates present with encephalopathy and a clinical history suggestive of prenatal or perinatal hypoxic-ischemic injury. Emerging evidence suggests that genetic conditions are frequently identified in cases of perinatal HIE; however, it is unclear which neonates with this diagnosis warrant genetic testing. This study will offer clinical genome sequencing to neonates with HIE who are undergoing total body cooling (therapeutic hypothermia) and their parents.
Conditions
- Hypoxic Ischemic Encephalopathy of Newborn
- Hypoxic Ischemic Encephalopathy
- Hypoxic Ischemic Encephalopathy (HIE)
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Genome sequencing | Neonates enrolled in this study will undergo genome sequencing with parental controls as applicable. |
Timeline
- Start date
- 2025-05-15
- Primary completion
- 2027-03-31
- Completion
- 2027-06-30
- First posted
- 2025-01-08
- Last updated
- 2025-10-01
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06762795. Inclusion in this directory is not an endorsement.