NCT06756854

Low-Level Laser Therapy and Injectable Platelet-Rich Fibrin for Thin Gingival Phenotype.

Evaluation of Low-Level Laser Therapy as Adjunctive to the Injectable Platelet-Rich Fibrin in the Management of Patients With Thin Gingival Phenotype.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: Faculty of Dental Medicine for Girls · Other Government
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Management of thin gingival phenotype using non-surgical methods (injection of liquid platelet rich fibrin and exposure to low level laser therapy

Detailed description

Thin gingival phenotype can lead to recession and root exposure. Liquid prf can be obtained by centrifugion of blood sample on speed 700 rpm for 3 min, then injection of this liquid in the attached gingiva and muco-gingival junction (3 times with 7 days interval) for the first group. The second group will be injected with I-PRF in the same method in addition to exposure to Low Level Laser therapy (after each injection of I-PRF). This method is expected to increase the thickness of the gingiva.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
BIOLOGICAL	Biologic Agent: injectable platelet rich fibrin.	injection of I-PRF to thin gingival phenotype 3 times with 7 days interval between sessions.
OTHER	injecable platelet rich fibrin, and low level laser therapy radiation.	injection of I-PRF+ exposure to LLLT to thin gingival phenotype 3 times with 7 days interval between sessions.

Timeline

• Start date: 2023-09-12
• Primary completion: 2024-05-14
• Completion: 2024-06-15
• First posted: 2025-01-03
• Last updated: 2025-01-03

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study