NCT06676826

Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen

Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen. A 12-month Multi-center Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: University of Bern · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

To compare the healing of intrabony periodontal defects treated with either open flap debridement and a volume-stable collagen matrix (VCMX) or a deproteinized bovine bone mineral with 10% collagen. The results will shed light on the clinical potential of VCMX in regenerative periodontal surgery and help to develop new treatment strategies.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
DEVICE	Infrabony defects will be filled with a volume-stable collagen matrix (VCMX)	Infrabony defects will be filled with a volume-stable collagen matrix
DEVICE	Infrabony defects will be filled treated with a deproteinized bovine bone mineral with 10% collagen	Infrabony defects will be filled with with a deproteinized bovine bone mineral with 10% collagen

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-09-30
• Completion: 2027-12-30
• First posted: 2024-11-06
• Last updated: 2025-10-06

Locations

1 site across 1 country: Switzerland