NCT06610604

Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Ming-an Yu · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment. This is a data collection study by allowing investigators to access information generated before and after treatment.

Detailed description

The incidence of thyroid nodules is rising worldwide. Papillary thyroid carcinoma (PTC), the most common type of thyroid cancer, has a favorable prognosis, with a low mortality rate and over 90% 10-year survival rate. Thyroidectomy is often applied to manage thyroid nodules as a traditional method. However, thermal ablation (TA), including microwave ablation (MWA), radiofrequency ablation (RFA), and laser ablation, has emerged as an alternative option for selected patients with thyroid function. TA methods are effective, safe, feasible, and have litter influence on thyroid function. Patients with thyroid nodules frequently exhibit higher levels of emotional stress compared to the general population. Additionally, health-related quality of life (QoL) has become an important endpoint and a strong predictor of survival time in medical and health research, underscoring the importance of treatments that not only prolong life but also preserve or enhance QoL. Considering the long survival time of patients with thyroid noduls and the similar therapeutic outcomes between surgery and MWA , it is crucial to pay more attention on patients\' QoL and emotional well-being before and after treatment.

Conditions

• Thyroid Nodule

Interventions

Type	Name	Description
PROCEDURE	thermal ablation	thermal ablation including microwave ablation, radiofrequency ablation of thyroid nodules
PROCEDURE	thyroidectomy	surgical resection of thyroid nodules

Timeline

• Start date: 2022-08-01
• Primary completion: 2027-06-01
• Completion: 2027-12-01
• First posted: 2024-09-24
• Last updated: 2024-09-24

Locations

1 site across 1 country: China