NCT06597071

Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely

Use of Oculometric Measures in the Differential Diagnosis of Typical and Atypical Parkinsonian Conditions: a Pilot Study

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: NeuraLight · Industry
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is an observational longitudinal study in 4 cohorts of patients with Parkinsonian syndromes, who are visiting the Movement Disorders outpatient clinics. The aim of the study is to assess the difference of oculometric measures in different neurodegenerative brain conditions and their accuracy over time, and as compared to clinical diagnosis, in order to find a change over time, difference between subgroups and correlations with accepted clinical endpoints in subjects who meet the inclusion criteria and who provide a signed Informed Consent.

Detailed description

As a part of the study, about 40 subjects will undergo a neurological evaluation including motor and cognitive assessments and a NeuraLight session including oculometric measurements and eye-tracking recordings using a novel software-based platform and an eye-tracking system (Tobii, CE-marked class B approved device). Test duration will be approx. 20 minutes. The oculometric evaluation will occur for at least 50% of the cohort 3 times (at baseline, at 6-months and at 12-month follow-up), and all subjects will be recruited over a period of 9 months. All assessments will be performed during a clinic visit unless authorized to be conducted remotely.

Conditions

• Parkinson Disease
• Progressive Supranuclear Palsy(PSP)
• Multiple System Atrophy

Interventions

Type	Name	Description
OTHER	NeuraLight PD	NeuraLight software-based platform for PD patients
OTHER	NeuraLight PSP	NeuraLight software-based platform for PSP patients
OTHER	NeuraLight MSA	NeuraLight software-based platform for MSA patients
OTHER	NeuraLight	NeuraLight software-based platform

Timeline

• Start date: 2024-09-10
• Primary completion: 2025-10-01
• Completion: 2025-12-01
• First posted: 2024-09-19
• Last updated: 2025-03-11

Locations

1 site across 1 country: Spain