NCT06579248

Intraoral Hypothermia Device for Preserving Taste During Radiation

Study of a Novel Intraoral Hypothermia Device for Preserving Taste During Radiation Therapy for Squamous Cell Carcinoma of the Larynx

• Status: Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Henry Ford Health System · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Radiation therapy to the head and neck region is known to cause taste dysfunction. Preliminary studies showed that cooling normal structures may lower damage caused by radiation. The purpose of this research study is to see if it is feasible to use an intraoral cooling device during radiation treatments to preserve or lower the decline of taste function.

Conditions

• Head and Neck Cancer
• Taste Dysfunction
• Radiation Therapy

Interventions

Type	Name	Description
DEVICE	Intraoral Device	Device that circulates cooled water through the oral cavity.

Timeline

• Start date: 2024-11-12
• Primary completion: 2026-08-30
• Completion: 2026-08-30
• First posted: 2024-08-30
• Last updated: 2026-01-14

Locations

1 site across 1 country: United States