NCT06563271

Approach to Ankle Sprains in the Emergency Department

Evaluation of Analgesic Treatments for Ankle Sprains in the Emergency Department

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Ankara Etlik City Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the short-term effects of routinely applied agents on pain and joint range of motion (ROM) in ankle sprains presenting to the emergency department (ED).

Detailed description

It is aimed to examine the effects of intravenous (IV) 50 mg dexketoprofen, IV ibuprofen 400mg and IV paracetamol 10 mg on pain and joint range of motion. To determine the effects of these agents on pain, the easily applicable Numerical Rating Scale (NRS) and Wong-Baker Faces Pain Rating Scale will be used. A standard handheld half-circle goniometer will be utilized to calculate active ankle joint ROM.

Conditions

• Ankle Sprains

Interventions

Type	Name	Description
DRUG	Dexketoprofen Trometamol 50 Mg/mL Solution for Injection	Dexketoprofen 50 mg administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUG	Ibuprofen 100 MG/ML Solution for Injection	Ibuprofen 100 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion). Group P: Paracetamol 10 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUG	Paracetamol 10 Mg/mL Solution for Injection	Paracetamol 10 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUG	isotonic saline	Ibuprofen and dexketoprofen will be administered intravenously (IV) by mixing them into 150 cc of isotonic saline.

Timeline

• Start date: 2023-12-01
• Primary completion: 2024-05-01
• Completion: 2024-06-01
• First posted: 2024-08-20
• Last updated: 2024-08-20

Locations

1 site across 1 country: Turkey (Türkiye)