NCT06549543

High-Intensity Laser Therapy: Effectiveness on Knee Osteoarthritis Patients

Additional Effect of High-Intensity Laser Therapy Over Conventional Physiotherapy Related to Pain and Function in Patients With Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled, 12-Week Follow-up Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Baskent University · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this prospective, randomized, double-blinded study is to investigate the additional benefits of high-intensity laser therapy (HILT) over conventional physiotherapy, related to pain and function, in patients with knee osteoarthritis (KOA).

Detailed description

The study was performed in Baskent University Physical Therapy and Rehabilitation Unit. 43 patients of both sexes, who were diagnosed clinical and radiographic knee osteoarthritis, with Kellgren Lawrence Grade 2 and 3, were randomly assigned in two groups. Group 1 (n = 21) received TENS, HP, exercises (EX), and High-Intensity Laser Therapy (HILT; Nd:yag laser, 10W). Group 2 (n = 22) received the same interventions but placebo HILT. All interventions were applied for 10 sessions. The Visual Analog Scale (VAS), Western Ontario \& McMaster Universities Osteoarthritis Questionnaire (WOMAC), and Lequesne Algofunctional Index (LAI) were performed before, after, and at 12-week follow-up.

Conditions

• Osteoarthritis, Knee

Interventions

Type	Name	Description
OTHER	High Intensity Laser Therapy	HILT is applied per session, with a maximum of 10.0 W, a mean of 5.7 W, a dose of 99 J/cm², and a total energy flux of 2079 J were applied over 6 minutes and 5 seconds on a 21 cm² field on the medial aspect of the knee joint.
OTHER	Transcutaneous Electrical Nerve Stimulation	TENS is an analgesic modality of physical therapy
OTHER	Hotpacks	Hotpacks is a thermoanalgesia modality of physical therapy
OTHER	SHAM - High Intensity Laser Therapy	for control group, sham HILT was applied, with lights on but no laser beam

Timeline

• Start date: 2022-04-01
• Primary completion: 2023-11-30
• Completion: 2024-02-01
• First posted: 2024-08-12
• Last updated: 2024-08-13

Locations

1 site across 1 country: Turkey (Türkiye)