NCT06545318

A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches

A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches: Validation Through a Clinical Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 115 (actual)
• Sponsor: Center of Innovation Technology & Reproductive Medicine · Industry
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men. The main questions it aims to answer are: Does the CA0 sperm selection device increases the sperm concentration? Does the CA0 sperm selection device increases the sperm motility? What are the differences in sperm membrane potential when CA0 is used? Do intracellular Calcium levels change when CA0 is used? Does CA0 increase fertilization rates? Researchers will compare CA0 to the standard of care for sperm selection (density gradient centrifugation) to see if CA0 has similar performance Participants will: Provide a semen sample Have their semen sample analyzed, processed and used for assisted reproduction technologies

Conditions

• Male Infertility

Interventions

Type	Name	Description
DEVICE	Density Gradient Centrifugation	Sperm separation with density gradients
DEVICE	CA0 chamber	Sperm separation with a novel device

Timeline

• Start date: 2023-01-01
• Primary completion: 2023-10-30
• Completion: 2023-11-15
• First posted: 2024-08-09
• Last updated: 2024-08-09

Locations

1 site across 1 country: Mexico