NCT06540651

Efficacy of Light Therapy in Treatment of Chronic Cluster Headache

Proof-of-concept Study on the Efficacy of Light Therapy in the Prophylactic Treatment of Chronic Cluster Headache

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Assistance Publique Hopitaux De Marseille · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cluster headache is a primary headache. The chronic form of the disease is often difficult to treat. It is now considered a chronobiological disease. This chronobiological character is based on clinical, biological and radiological arguments. This study focuses on the use of light therapy in cluster headache. Light therapy has already been used in the treatment of other chronobiological diseases, such as seasonal depression, but also recently in the therapy of other primary headaches (such as migraine). Its aim is to re-adjust chronobiological rhythms, and it therefore seems worth testing in the chronic form of cluster headache. Light therapy is delivered to the patient using a consumer electronics device.The main objective is to evaluate the prophylactic efficacy of light therapy in patients with chronic cluster headache.

Conditions

• Cluster Headache

Interventions

Type	Name	Description
OTHER	use of Luminettes ® with active light emission	Spectrum of 400 \< X \< 750 nm assumed active
OTHER	use of Luminettes ® with a light emission presumed to have no therapeutic effect	Modification of spectrum parameters for wavelengths covered, with light emission in a spectrum of 560 \< X \< 650 nm assumed to have no therapeutic effect

Timeline

• Start date: 2025-02-06
• Primary completion: 2027-02-05
• Completion: 2027-05-05
• First posted: 2024-08-06
• Last updated: 2025-03-17

Locations

2 sites across 1 country: France