NCT06537648

Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

The investigators are assessing acceptability, appropriateness, and feasibility of an remote choreographed exercise intervention using validated scales alongside qualitative data among young adults with Down Syndrome. Participants will take part in a 12-week exercise program with two 35-minute session per week delivered in a group setting. The aims of the project are to: * Assess the feasibility of a 12 week remotely delivered group dance intervention. * Assess changes in aerobic fitness and cognitive function in response to a 12 week remotely delivered group dance intervention. * Assess the intensity and total energy expenditure of remotely delivered group dance sessions.

Detailed description

The incidence of Alzheimer's disease for persons with Down syndrome exceeds 90%, and physical activity engagement has demonstrated potential to delay onset of Alzheimer's disease for this population. Adults with Down syndrome participate in less physical activity than their counterparts without disability, partially due to unique barriers preventing engagement in typical modalities of physical activity for this population. Dance, which is characterized by rhythmic physical movements offers the potential for social engagement, and stimulation of brain functions may offer a reasonable alternative to traditional physical activity modalities. However, empirical evidence to support the feasibility of a remotely delivered group dance intervention and evaluation of the intensity and energy expenditure achieved by a dance intervention for adults with Down syndrome are currently unavailable and will be the focus of the proposed pilot trial. Adults with Down will be asked to attend 35 minute remotely delivered (Zoom®) group dance sessions twice weekly across 12 weeks to assess the acceptability, appropriateness, and feasibility of the intervention, energy expenditure achieved during the exercise sessions, and evaluate change in aerobic fitness and cognitive function after 12 weeks.

Conditions

• Down Syndrome
• Physical Inactivity

Interventions

Type	Name	Description
BEHAVIORAL	Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome Program	Adults with Down syndrome will be asked to attend 35 minute, remotely delivered (Zoom®) group dance sessions twice weekly across 12 weeks. All sessions will be directed by an instructor experienced in leading 35 minute, group remote exercise sessions for individuals with intellectual disability as part of the ongoing exercise program for individuals with intellectual disability offered by the Division for Physical Activity and Weight Management.

Timeline

• Start date: 2024-08-02
• Primary completion: 2025-05-09
• Completion: 2025-05-09
• First posted: 2024-08-05
• Last updated: 2026-03-13
• Results posted: 2026-03-13

Locations

1 site across 1 country: United States