NCT06532734

Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype

Presence of Barrett's Esophagitis in a Cohort of People With Eating Disorders Who Engage in Purging Behaviors: A Pilot Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 25 (estimated)
• Sponsor: Denver Health and Hospital Authority · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors

Detailed description

A prospective cohort study to assess the presence of BE in those with purging behaviors from their eating disorders has not been completed. There are multiple case reports describing a younger population not meeting typical screening guidelines whom developed this condition. To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors. Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting the current screening guidelines for BE will still test positive for BE.

Conditions

• Barrett Esophagus
• Anorexia Nervosa, Binge Eating/Purging Type
• Rumination
• Vomiting
• Eating Disorders
• Esophageal Adenocarcinoma

Interventions

Type	Name	Description
DEVICE	EsoGuard	device used to collect esophageal cell samples to test for the presence of abnormal cells which may indicate a dx of Barrett's esophagitis.

Timeline

• Start date: 2024-11-12
• Primary completion: 2026-11-01
• Completion: 2026-11-01
• First posted: 2024-08-01
• Last updated: 2025-12-10

Locations

3 sites across 1 country: United States

Regulatory

• FDA-regulated device study