Trials / Enrolling By Invitation
Enrolling By InvitationNCT06526078
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
A Brief Automated Neurocognitive Training to Enhance the Real-World Impact of Ketamine's Rapid Antidepressant Effect
- Status
- Enrolling By Invitation
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 600 (estimated)
- Sponsor
- University of Pittsburgh · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
In a sample of patients already receiving ketamine (or esketamine) treatment as part of their clinical care, this project seeks to test whether we can enhance and/or extend (es)ketamine's rapid effects by introducing helpful information delivered by a computer-based cognitive training protocol. This work could ultimately lead to the ability to treat depression more efficiently and with broader dissemination by rapidly priming the brain for helpful forms of learning.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Cognitive Training | Sessions of cognitive training exercises (15-20min each) self-administered via a web app |
| BEHAVIORAL | Sham Training | Sessions of sham training exercises (15-20min each) self-administered via a web app |
Timeline
- Start date
- 2024-11-12
- Primary completion
- 2029-05-31
- Completion
- 2029-05-31
- First posted
- 2024-07-29
- Last updated
- 2025-11-21
Locations
3 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06526078. Inclusion in this directory is not an endorsement.