NCT06523075

Host Dysregulation-Driven Sepsis Prediction Model

Construction and Validation of a Sepsis Prediction Model Based on Dysregulation of Host Response

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (actual)
• Sponsor: Second Affiliated Hospital of Wenzhou Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The aim of this study is to identify risk factors associated with sepsis and to construct a predictive model for sepsis. This will provide an objective theoretical and empirical foundation for the diagnosis, assessment, and management of sepsis in our country.The primary questions addressed are: What are the risk factors for the development of sepsis? How do we improve the prognosis of sepsis?

Conditions

• Sepsis

Interventions

Type	Name	Description
OTHER	Tumor Necrosis Factor	This study is a retrospective observational study, with Tumor Necrosis Factor being one of the exposure factors under investigation.
OTHER	Interleukin-1β	This study is a retrospective observational study, with Interleukin-1β being one of the exposure factors under investigation.
OTHER	Interleukin-12	This study is a retrospective observational study, with Interleukin-12 being one of the exposure factors under investigation.
OTHER	Interleukin-18	This study is a retrospective observational study, with Interleukin-18 being one of the exposure factors under investigation.
OTHER	Complement C3	This study is a retrospective observational study, with Complement C3 being one of the exposure factors under investigation.
OTHER	Complement C5	This study is a retrospective observational study, with Complement C5 being one of the exposure factors under investigation.

Timeline

• Start date: 2024-09-01
• Primary completion: 2024-10-13
• Completion: 2024-10-17
• First posted: 2024-07-26
• Last updated: 2024-10-31

Locations

2 sites across 1 country: China