NCT06507280

The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Aydin Adnan Menderes University · Academic / Other
• Sex: All
• Age: 11 Years – 14 Years
• Healthy volunteers: Accepted

Summary

This study aims to determine the levels of NLRP3, caspase-1 and IL-1β concentrations in the gingival crevicular fluid of paediatric patients with gingivitis and their changes after periodontal treatment.

Detailed description

After being informed about the study and potential risks, necessary periodontal measurements will be performed and gingival crevicular fluid will be collected from all patients who gave written informed consent, and patients with gingivitis will be followed up on the 7th and 30th day after periodontal treatment.

Conditions

• Gingivitis

Interventions

Type	Name	Description
PROCEDURE	Periodontal theraphy	periodontal therapy

Timeline

• Start date: 2024-02-01
• Primary completion: 2024-09-01
• Completion: 2025-01-01
• First posted: 2024-07-18
• Last updated: 2024-07-18

Locations

1 site across 1 country: Turkey (Türkiye)