NCT06499753

Differences in Dry Eye Symptoms Related to Geographic Location in Spain and Impact of Artificial Tears Use

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,033 (actual)
• Sponsor: University of Valladolid · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

This study assessed the differences in DED symptomatology measured with the OSDI questionnaire regarding climate data of the geographic location in a large population in Spain, with a special focus on the relative humidity (RH) of the place of residence and the impact of artificial tears use, to help eye care practitioners in patient management and education

Detailed description

This was a multicentre study enrolling patients to attend primary eye care centres of the EMO research group across 12 different Spanish locations. A comprehensive eye examination was performed in all participants. Dryness symptomatology was assessed with OSDI questionnaire. In subjects with dryness symptomatology (OSDI questionnaire score between 13 and 32) were prescribed to use high molecular weight HA-based artificial tears (DISOP Inc, Spain) along three months), instilled 3 times per day. Additionally, the daily mean, minimum, and maximum values of the climate data for five different variables \[skin temperature (°C), wind gusts (m/s), air temperature (°C), atmospheric pressure (Pa) and RH (%)\] corresponding to the visit date were collected from the EU-funded Copernicus Climate Change Service and the 5-year average RH values published by the Spanish meteorological agency.

Conditions

• Dry Eye Syndromes
• Hyaluronic Acid
• OSDI

Interventions

Type	Name	Description
OTHER	high molecular weight HA-based artificial tears	use of high molecular weight HA-based artificial tears three times per day

Timeline

• Start date: 2020-02-01
• Primary completion: 2020-11-30
• Completion: 2022-01-31
• First posted: 2024-07-12
• Last updated: 2024-07-17

Locations

1 site across 1 country: Spain