NCT06480825

Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

Ulta-High Frequency Ultrasound Assessment of Normal Versus Gingivitis Affected Gingival Tissues

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: University of Pisa · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis. Clinically, localized signs of inflammation limited to the gingiva, presence of significant bacterial plaque load, and stable attachment levels on the periodontium can be observed in course of gingivitis. The aim of the present study is to compare clinical aspects of gingival tissue in healthy patients versus patients with gingivitis to assess the ultrastructural variations present in course of inflammation. Patients with gingivitis and healthy controls will be enrolled. All patients will undergo ultra-high frequency ultrasonographic scans (70 MHz) of gingival tissue on three areas per dental arch (anterior, middle right, middle left). Gingival thickness, echogenicity, and vascularization assessed through resisitive index will be evaluated.

Conditions

• Gingivitis
• Periodontitis

Interventions

Type	Name	Description
OTHER	Performance of ultrasonographic scan	Ultra-high frequency ultrasonographic scan of gingival tissues

Timeline

• Start date: 2024-04-02
• Primary completion: 2026-01-31
• Completion: 2028-07-01
• First posted: 2024-06-28
• Last updated: 2026-04-01

Locations

2 sites across 1 country: Italy