NCT06437067

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

A Real-world Study on the Long-term Prognosis of Acute-on-chronic Liver Failure

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Qin Ning · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The subjects of this study were inpatients with ACLF who were admitted to Tongji Hospital in Wuhan from March 2023 to June 2025. After patients were enrolled, The patient's general information (gender, age, past medical history, etc.), complications (ascites, hepatic encephalopathy, hepatorenal syndrome, gastrointestinal bleeding, etc.), laboratory tests (CRP, PCT, INR, WBC, fungal/bacterial diagnostic tests, etc.), symptoms and signs at the time of infection, and at admission (D1), D4, D7, D14, D21, etc.) were recorded Save the blood separately. The patients were divided into fungal infection group, bacterial infection group and non-infection group according to the infection status after admission.

Conditions

• Acute-On-Chronic Liver Failure

Timeline

• Start date: 2023-03-01
• Primary completion: 2024-12-31
• Completion: 2025-06-30
• First posted: 2024-05-31
• Last updated: 2024-05-31

Locations

1 site across 1 country: China