NCT06429514

Study on the Mechanism of Ganoderma Lucidum Spore Powder in the Treatment of Depression

Based on the Theory of Gut-brain Axis, the Intervention Effect and Related Mechanism of Ganoderma Lucidum Spore Powder on Depressive Symptoms in Patients With Thyroid Cancer Were Investigated

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 298 (actual)
• Sponsor: Ling Zhiqiang · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To clarify the clinical effect of Ganoderma lucidum spore powder intervention on postoperative depressive symptoms of papillary thyroid carcinoma ; to elucidate the antidepressant mechanism of Ganoderma lucidum spore powder.

Detailed description

After being informed of the study and potential risks, all patients who gave written informed consent were enrolled. A total of 300 eligible patients were randomly assigned in a double-blind manner and divided into experimental group and control group at a ratio of 2 : 1. The subjects were given oral test drugs ( Ganoderma lucidum spore powder or placebo ) 4g per day for 90 days from the first day after enrollment.

Conditions

• Depression
• Thyroid Cancer

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ganoderma lucidum spore powder	One bag at a time, 2 times a day, 2g / bag
OTHER	placebo	One bag at a time, 2 times a day, 2g / bag

Timeline

• Start date: 2023-03-28
• Primary completion: 2024-05-03
• Completion: 2024-05-03
• First posted: 2024-05-28
• Last updated: 2024-05-28

Locations

1 site across 1 country: China