NCT06380855

Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The investigators propose to use flexible endoscopy combined with transanal total mesorectal resection to further reduce anal injury.

Detailed description

Endoscopic technique has become an indispensable part of Natural orifice transluminal endoscopic surgery (NOTES). However, the upper gastrointestinal tract is easy to cause severe leakage complications, which mainly limits the application of endoscopy in rectum. Herein, investigators propose purse suture closing distal rectum and full-layer incision of the rectal wall using flexible endoscopic from anal to assist in hybrid transanal total mesorectal resection (taTME).Further reduce the damage of anus caused by taTME.

Conditions

• Rectal Cancer

Interventions

Type	Name	Description
PROCEDURE	Flexible colonoscope assisted hybrid transanal total mesorectal resection	Endoscopic pursestring suture (EPSS) was performed at the distance from 1cm to the inferior edge of the tumor by a double-channel flexible colonoscope. An endoloop was inserted through one channel. Meanwhile, the endoclips was inserted through the other channel one by one to fix the endoloop around the rectal wall. And then the endoloop was tightened slowly. After completing the routine lavage lumen, a full-thickness, circumferential dissection was performed by flexible colonoscope following taTME surgical principle until it converged with the laparoscopy group.

Timeline

• Start date: 2022-08-24
• Primary completion: 2025-08-24
• Completion: 2025-08-24
• First posted: 2024-04-24
• Last updated: 2024-04-24

Locations

1 site across 1 country: China