Trials / Recruiting
RecruitingNCT06356272
Oropharynx (OPX) Biomarker Trial
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 440 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this research is to identify a biomarker that is exists when human papillomavirus (HPV) mediated oropharyngeal squamous cell carcinoma is present and does not exist when HPV mediated oropharyngeal squamous cell carcinoma is absent.
Detailed description
PRIMARY OBJECTIVE: I. To identify a biomarker (or biomarkers) that is present when disease is present (i.e., at diagnosis or recurrence) and not present when disease is absent (i.e., after treatment, in HPV negative patients or in normal controls). OUTLINE: This is an observational study. Patients undergo blood sample collection, saliva sample collection, complete questionnaires and have their medical records reviewed on study.
Conditions
- Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
- Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
- Metastatic Oropharyngeal Squamous Cell Carcinoma
- Oropharyngeal Squamous Cell Carcinoma
- Recurrent Oropharyngeal Squamous Cell Carcinoma
- Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
- Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
- Head and Neck Carcinoma
- Head and Neck Neoplasm
- Salivary Gland Neoplasms
- Thyroid Gland Neoplasm
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Non-Interventional Study | Non-interventional study |
Timeline
- Start date
- 2019-11-15
- Primary completion
- 2029-11-30
- Completion
- 2029-11-30
- First posted
- 2024-04-10
- Last updated
- 2025-11-05
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06356272. Inclusion in this directory is not an endorsement.