NCT06351696

The Effects of Bromelain Supplement in Patients With Ulcerative Colitis

The Effects of Low FODMAP Diets Accompanied With and Without Bromelain Supplement on Quality of Life, Disease Activity Index and Inflammation in Patients With Ulcerative Colitis With and Without Primary Sclerosis Cholangitis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 84 (estimated)
• Sponsor: National Nutrition and Food Technology Institute · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

In this study, patients with active mild to moderate UC with or without PSC will be randomized to receive either bromlein or placebo along with low FODMAP diet for 8 weeks. IBDQ, SCCAIQ, CRP, TAC, TNF-a will be measured before and after the intervention.

Conditions

• Ulcerative Colitis
• Primary Sclerosing Cholangitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Bromlein	1500 mg/day
OTHER	Placebo	Placebo (1500 mg/day)

Timeline

• Start date: 2024-04-20
• Primary completion: 2024-07-20
• Completion: 2024-08-10
• First posted: 2024-04-08
• Last updated: 2024-04-09

Locations

1 site across 1 country: Iran