NCT06340646

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 990 (estimated)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The overall goal of the WU-PE-CGS is to build a rigorous, scientific evidence base for approaches that direct engagement of cancer patients and post-treatment cancer survivors as participants in cancer research, and to investigate the impact of directly engaging participants in decisions regarding returning of genomic results on participants' health and satisfaction. Participants in this study will be presented with the choice of types of genomic results to receive, and the Engagement Optimization Unit (EOU) will investigate the impact of this intervention on participant knowledge, expectations of benefit, personal utility, and decisional conflict.

Conditions

• Cholangiocarcinoma
• Multiple Myeloma
• Colon Cancer
• Rectal Cancer

Interventions

Type	Name	Description
OTHER	Return of Genetic Results: Biomarker information from cancer cells	Participants will receive a novel return of results report that is tailored to their choices.
OTHER	Return of Genetic Results: Inherited mutations related to cancer	Participants will receive a novel return of results report that is tailored to their choices.
OTHER	Return of Genetic Results: Inherited mutations related to other medical issues	Participants will receive a novel return of results report that is tailored to their choices.

Timeline

• Start date: 2022-10-18
• Primary completion: 2027-01-31
• Completion: 2027-01-31
• First posted: 2024-04-01
• Last updated: 2025-07-11

Locations

1 site across 1 country: United States