NCT06327633

Effects of Olfactory Training on the Brain Function in T2DM Patients With Mild Cognitive Impairment

A Pilot, Prospective, Randomized, Open Label, Parallel, 4-month Study to Explore and Evaluate the Therapeutic Effects of Olfactory Training on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in T2DM Patients With Mild Cognitive Impairment.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective, randomized, open label, parallel, 4-month study to explore and evaluate the therapeutic effects of olfactory training on the cognitive function, olfactory function, and odor-induced brain activation in T2DM patients with mild cognitive impairment (MCI).

Conditions

• Type 2 Diabetes Mellitus
• Mild Cognitive Impairment

Interventions

Type	Name	Description
OTHER	Olfactory Training	The subjects repeatedly sniffed pleasant scents of rose, lemon, clove, eucalyptus, coffee and cinnamon twice a day, 6-min per time, with focus, until the completion of the study.

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-05-15
• Completion: 2025-05-15
• First posted: 2024-03-25
• Last updated: 2025-07-11

Locations

1 site across 1 country: China