NCT06325969

PCOS Patients' Immune Alterations

Evaluation of Immune Status in Patients With Polycystic Ovary Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 162 (actual)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

In this study, the investigators will include PCOS patients and healthy women who meet the trial criteria from the clinical research centers of 3 hospitals, introduce the content of this study to participants, and invite participants to participate. Flow cytometry was used to detect the immune function of peripheral blood samples of PCOS patients, to clarify the immune function characteristics of PCOS patients, and to try to establish an evaluation method of the immune function of PCOS patients.

Detailed description

PCOS patients and healthy women were recruited in outpatient clinics of three hospitals, and peripheral blood was retained for flow cytometry after completing relevant examinations. In this study, flow cytometry was used to detect the antigenic antibody reaction between the surface differentiation antigen of lymphocyte membrane and fluorescence-labeled antibody in human peripheral blood, and the unlabeled cells were dissolved. The number and percentage of cell groups expressing different markers were counted by the fluorescence detection system on flow cytometry.

Conditions

• Polycystic Ovary Syndrom
• Metformin
• Immune Function

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Detect the immune function of peripheral blood samples	Flow cytometry was used to detect the immune function of peripheral blood samples of PCOS patients.

Timeline

• Start date: 2023-11-03
• Primary completion: 2025-07-10
• Completion: 2025-07-10
• First posted: 2024-03-22
• Last updated: 2025-07-11

Locations

1 site across 1 country: China