NCT06311253

Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash

Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash: Randomized Clinical Trial

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Pavia · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to assess the effect of lactoferrin in LBC complex can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients.

Detailed description

The aim of the study is to assess the effect of lactoferrin in LBC complex can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients. Patients' enrollment will be conducted according to inclusion criteria. At the first visit, periodontal parameters will be recorded: Plaque Index (PI), recession (R) Bleeding on Probing (BoP), modified Marginal Gingival Index (mMGI), Papillary Marginal Gingival (PMGI), Plaque Control Record ( PCR %), Approximal Plaque Index (API), Clinical Attachment loss (CAL) and Probing Pocket Depth (PPD). Professional debridement will be conducted with piezoelectric instrumentation and air-flow administration with glycine powders. Subsequently, patients will be randomly divided into two groups: \- the Trial group, in which patients will perform home oral hygiene with Emoform Glic toothpaste + mouthwash twice a day the Control group, in which patients will perform home oral hygiene with Emoform Glic toothpaste twice a day. Professional debridement will be repeated every 3 months. Periodontal indexes evaluation will be conducted at the baseline (T0), after 1 month (T1), after 3 months (T2), and after 6 months (T3).

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
OTHER	Emoform Glic Toothpaste	Daily use of Emoform Glic toothpaste twice a day during home oral hygiene
OTHER	Emoform Glic Mouthwash	Daily use of Emoform Glic mouthwash twice a day during home oral hygiene

Timeline

• Start date: 2024-03-20
• Primary completion: 2025-09-01
• Completion: 2025-09-01
• First posted: 2024-03-15
• Last updated: 2025-01-22

Locations

1 site across 1 country: Italy