NCT06307041

Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters

Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters: A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Özlem SARAÇ ATAGÜN · Academic / Other
• Sex: All
• Age: 18 Years – 47 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to evaluate the effects of 0.2% HA-impregnated dental flosses on the clinical periodontal parameters of patients with gingivitis.

Detailed description

Gingivitis is a common inflammatory lesion caused by the build-up of oral biofilm and is an essential precursor to periodontitis. For its treatment, oral hygiene habits, such as dental flossing, must be improved, and adjunctive materials, such as hyaluronic acid, may be used to reduce plaque formation and gingival inflammation. This study aimed to assess the effects of 0.2% hyaluronic acid gel (Gengigel®)-impregnated dental flosses on the clinical periodontal markers of patients with gingivitis. This clinical study adopted a split-mouth, randomized controlled trial design. After clinical data were assessed at baseline, and supragingival scaling and planing was performed, bilateral gingivitis regions were randomly allocated to either a test group (hyaluronic acid gel-impregnated floss) or a control group (regular floss) using a computer-generated randomization table. Clinical parameters were recorded at 1, 2, and 4 weeks after treatment.

Conditions

• Gingivitis

Interventions

Type	Name	Description
DEVICE	Dental floss+Gengigel	0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses
DEVICE	Dental Floss	Dental Flosses

Timeline

• Start date: 2023-04-03
• Primary completion: 2023-07-07
• Completion: 2023-08-11
• First posted: 2024-03-12
• Last updated: 2024-03-12

Locations

1 site across 1 country: Turkey (Türkiye)