Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06305676

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

Status
Recruiting
Phase
Study type
Observational
Enrollment
400 (estimated)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

Investigators seek to determine the sensitivity and specificity of a combined HPV 16 DNA and host gene methylation oral biomarker panel to distinguish early Oropharyngeal Cancer (OPC) cases from controls among 100 early and 100 late disease pre-treatment OPC cases, and 200 controls matched by sex, age, race/ethnicity, and tobacco use collected from the Moffitt Cancer Center (Moffitt) and the University of Pittsburgh Medical Center Hillman Cancer Center (Pittsburgh).

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTcombined HPV 16 DNA and host gene methylation oral biomarker panelDNA Methylation Profiling

Timeline

Start date
2024-01-22
Primary completion
2029-01-01
Completion
2029-01-01
First posted
2024-03-12
Last updated
2026-02-09

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT06305676. Inclusion in this directory is not an endorsement.